O-Shot® vs. Estrogen Cream for Vaginal Dryness and Pain (Dyspareunia)

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Vaginal dryness and pain during intimacy — known medically as dyspareunia — are common concerns for women, especially after menopause. Traditionally, topical estrogen creams have been the go-to treatment, but what about women who cannot or prefer not to use hormones?

Recent research suggests that the O-Shot®, a platelet-rich plasma (PRP) treatment, may offer an equally effective — or even slightly superior — alternative.

🌸 What the Studies Show

Several years ago, researchers used PRP injections (prepared using Regen kits, the same technology we use today) in women experiencing painful intercourse after menopause — including those with a history of breast cancer who could not take estrogen. Results showed significant improvement in comfort and sexual function after PRP treatment, without any added hormone exposure.

More recently, a study from Turkey directly compared PRP injections with topical estrogen cream in 66 postmenopausal women suffering from vaginal atrophy and pain. Half received estrogen, while the other half — who had not responded to estrogen — received PRP instead.

After 12 weeks, both groups showed improvement, but the PRP group reported slightly better results on the Female Sexual Function Index, a standard measure of sexual health and comfort.

💉 Why PRP May Be the Better Choice

Even if PRP works just as well as estrogen cream, it offers several important advantages:
• Non-hormonal — safe for women with a history of breast cancer or those avoiding estrogen.
• Natural healing — uses your body’s own growth factors to regenerate healthy vaginal tissue.
• Additional benefits — many women also notice improvements in urinary control and overall sensitivity.

✨ The Bottom Line

Both estrogen creams and PRP can help relieve dryness and pain, but the O-Shot® provides a natural, regenerative option that avoids the risks of hormone therapy and may enhance other aspects of intimate wellness.

If you’ve been struggling with vaginal discomfort — especially if estrogen creams haven’t helped — the O-Shot® may be a safe and effective next step toward restoring comfort, confidence, and pleasure.

📍 Learn more or book a private consultation at Biomed Natural Health.

 

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