Platelet-Rich Plasma (PRP) has gained attention in recent years for its regenerative effects in dermatology and women’s health — especially in treating chronic inflammatory skin conditions like Lichen Sclerosus and Lichen Planus. But how does it compare to conventional treatments such as corticosteroids?
🌿 PRP and Lichen Sclerosus
Lichen Sclerosus is a chronic inflammatory condition that affects the skin, often in the genital area, causing itching, pain, and thinning of tissue.
Multiple clinical studies have now demonstrated that PRP therapy can significantly improve symptoms and skin texture by stimulating natural tissue repair and reducing inflammation. In fact, nearly every published study to date has shown positive outcomes with PRP for Lichen Sclerosus — with improvements confirmed both symptomatically and under biopsy.
There was one outlier study that found no significant difference between PRP and placebo, but interestingly, the placebo used was saline, which itself may have therapeutic effects due to tissue hydration and micro-needling–like stimulation. Even in that study, over 50% of participants improved — suggesting the results may have been influenced by the “placebo” itself.
💉 PRP and Lichen Planus
When it comes to Lichen Planus, the evidence is more mixed. Some studies have found PRP to be as effective as corticosteroid injections in reducing inflammation and discomfort, while others suggest little difference between the two. Corticosteroids remain a reliable first-line treatment, but PRP may be a useful natural, regenerative alternative, particularly for patients seeking to avoid long-term steroid use or those with recurrent symptoms.
⚖️ The Bottom Line
PRP appears consistently effective for Lichen Sclerosus and shows potential benefits for Lichen Planus, though more research is needed. Unlike corticosteroids, PRP uses your body’s own platelets to trigger healing, offering a natural and low-risk therapy that supports tissue repair from within.
📍 To learn more about regenerative options for chronic inflammatory skin and mucosal conditions, visit Biomed Natural Health.
