When it comes to Platelet-Rich Plasma (PRP) therapy, timing might be more important than we think.
A recent study has revealed that platelet levels in the blood fluctuate throughout the day, suggesting that the time of your PRP blood draw could influence the quality and potency of the treatment.

Your Platelets Have a Rhythm Too

According to research, platelet counts in whole blood follow a circadian rhythm — meaning they rise and fall naturally over the course of a day.
The findings showed:
• Higher platelet levels were observed around noon and 4:00 PM
• Lower levels tended to occur early in the morning

This means that drawing blood for PRP later in the day could potentially result in a richer concentration of platelets and growth factors, possibly enhancing the regenerative effect of the treatment.

What Else Affects PRP Quality?

Time of day isn’t the only variable.
Previous studies have shown several other factors can influence PRP composition and effectiveness, including:
• Exercise: Drawing blood right after aerobic activity can temporarily change platelet activity.
• Fasting: Long fasting periods may reduce certain blood components important for PRP.
• Diet: Protein intake and overall nutrition can impact platelet health and growth factor release.

Together, these findings remind us that the body’s internal environment matters — and optimizing it before treatment could make PRP therapy even more effective.

What This Means in Practice

While the difference may be subtle for some patients, it’s an important insight for clinicians and practitioners who want to maximize the healing potential of PRP.
If you have flexibility in scheduling, midday appointments might offer a small but meaningful advantage in platelet concentration and growth factor activity.

At BioMed Natural Health, we continuously monitor new research like this to refine how we deliver regenerative therapies — ensuring every treatment is aligned with your body’s natural rhythms for optimal recovery and rejuvenation.